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Pyridies are a skin disease prevention and control drug, mainly used to treat acne, macular spots and melanin deposition of the skin. It is also an important organic synthetic intermediate, in plastics, rubber and other industries for the synthesis of plasticizers, in aviation oil for the synthesis of low-temperature high-speed lubricants, electrolytic capacitor manufacturing and other important applications. The use of oleic acid and other unsaturated fatty acids, as well as castor oil, cotton oil and other corresponding triglyceride preparation of glycerine is the main production method.
Pharmacological effects
Pyridies have anaerobic and aerobic bacteria that inhibit or kill skin areas. In vivo tests showed that the local application of sterilized cream, for 2 to 3 consecutive months, has significantly reduced the number of skin bacteria and the genus aprofloxacin in the hair follicles, indicating that this product has a direct antibacterial effect. In addition, local application of pyridies can reduce the skin surface free fatty acids and lipid composition. The anti-keratification effect on the skin of normal people or acne patients is mainly due to reducing the synthesis of filament keratin, thereby reducing hair follicle keratin over-curvying. Pyridies selectively act on abnormal melrome cells to inhibit their excessive activity. Therefore, local application of longer-term cytric acid can reduce the production of melanin skin in elderly plaque patients. However, this product has no de-pigmentation effect on the pigment of normal skin. Pyridic acid also has anti-cell proliferation and anti-cytotoxic effect, the principle of action mainly by destroying mitochondrial respiratory pathways and cell DNA synthesis.
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